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Sixty elderly men were put on various Ostarine dosages for 3 months, and it was found that simply taking 3mg of Ostarine per day led to an increase in muscle mass by 1g and total daily protein intake by approximately 40g. 6-hydroxy-2-deoxyuridine It appears from some experimental work that oral supplementation of 6OH-deoxyuridine (6-OHD) might be a fairly effective weight loss supplement. Subjects were assigned to one of five groups for 12 weeks. At the three-month assessment the mean change in bodyweight at baseline was reduced by 2.2g (p < 0.05). This result correlated with an improvement in serum total cholesterol, waist circumference, fasting insulin, and free testosterone. However, the change in bodyweight was still greater than that of the placebo group. On the 4- and 6-month assessments, no significant weight change was seen in any group (p > 0.05). There appears to be only a small placebo effect associated with the supplement. Phenyl-arginine One of the most promising studies on the effects of pyrimidine hydrochloride on muscle protein has been conducted in young rats. Two groups of male Wistar rats were given either 0.1 or 2mg pyrimidine to a bodyweight of 21 g/animal for 12 weeks. No reduction in body mass was found in either group, and the study has also been replicated in female rats, but the results have not yet been established. Trial Data in the field of osteoblast support The evidence does not support the benefits of the use of bone-mobilizing compounds, such as L-arginine, in reducing symptoms of osteoporosis. In fact, there is little or no evidence of any health benefits from osteoporosis treatments, and it may even be a contributing factor to higher mortality rates among osteoporosis patients. Some research has demonstrated that L-arginine supplementation is superior to L-citrulline on reducing the bone fracture rate in postmenopausal women. L-arginine has been shown to improve markers of bone turnover in postmenopausal women. However, there have been no studies using humans or animal models of osteoporosis or to test the effect of L-arginine supplementation on a person's bone mineral density, with the exception of one study that examined the effects of 200mg of L-arginine, orally or by injection. The report states that the men in that study had low bone mineral density and bone loss, but the study lacked statistical power and should be interpreted with caution. Related Article: